ASP.NET 2.0 web application errors on first touch

I have a new Windows Vista laptop which is working really nicely. However, I noticed that when I use Visual Studio 2008 to develop ASP.NET web applications with the ASP.NET Development Server (that comes with Visual Studio), I always get the error message shown next when I first launch the application. But once I hit Refresh in my web browser, the problem goes away. The error is:

System.IO.DirectoryNotFoundException: Could not find a part of the path 'C:\Windows\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files'.

So far, I haven't had the chance to investigate this error, but I assume it must be either an antivirus issue, or then related to CodeGear Delphi, as the stack trace includes a hint about Borland.DbkAsp.DbkConnModule. Lets see when I have the time to check this out.